Free Radical Research (Special Issue available in open access)

IFRA 185 239

Knowledge of chemical reactivity is essential for understanding at a molecular level the mechanistic steps that drive processes in life sciences. The aims of the COST Action CM1201 have focused on the role of chemistry as a central discipline for understanding free radical biological events through the implementation of biomimetic chemical models. The Action subject of “Biomimetic Radical Chemistry” developed research activities into four areas organized in working groups: (WG1) Radical Enzymes; (WG2) Models of DNA damage and consequences; (WG3) Membrane stress, signalling and defences; (WG4) Bio-inspired synthetic strategies.

This COST Action has realized an effective networking, starting from December 2012 and lasting four years, triggering multidisciplinary collaborations of the free radical scientific community with specialized research areas in chemical, biological, and medical subjects, producing new knowledge and targeting new applications. Another aim of the Action has been to gather a substantial amount of competences and know-how, either for dissemination and utilization in research and innovation, in particular for the formative experience of early stage researchers and the build-up of their career with an interdisciplinary background.

Numerous collaborations took place among the participating 80 research teams of the Action and its Working Groups. The Memorandum of Understanding was signed by 24 participating countries, as well as shared with two COST Near Neighbor Countries and two International Partner Countries. The Working Group leaders will give a brief description of the achievements in the four thematic areas, offering an overview of ongoing free radical research in a very attractive and multidisciplinary context.

The Special Issue of Free Radical Research on “Biomimetic Radical Chemistry” and the papers published herein demonstrate the strong intention to collaborate that animated all participants and determined the success of the Action.

Uni bern 2017/02