Working Group 1: Radical Enzymes

Many biological processes use reactions catalysed by radical enzymes, e.g. biosynthetic processes leading to antibacterial agents and cofactors. Besides their medical importance, radical enzymes are crucial for the environmental degradation of aliphatic (e.g. hexane) and aromatic hydrocarbons (e.g. naphthalene). The primary objectives of this WG will be:

  • To elucidate the catalytic pathways and mechanisms of selected radical enzymes.
  • To discover new radical enzymes.
  • To develop model systems and biomimetic chemistry based on the pathways used by radical enzymes.

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